Alternative Methodologies Used in Animal Research
If potentially painful / distressful procedures are proposed on the protocol form, the PI is required to document that there are no less painful / distressful procedures to accomplish the goals of the project. Further, if there are less painful / distressful procedures to accomplish the aims of the project, the PI must provide a scientific justification for not using the less painful approach. The documentation process can be reasonably accomplished with a literature search that includes at least one of the "Alternatives" database. Please use the resources below to help with your searches.
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Additional Sites
Educational Use of Animal-Based Labs
The Use of Animals in Higher Education: Problems, Alternatives, and Recommendations
Animal Use Alternatives Thesaurus
The Netherlands Center for Alternatives to Animal Use
Microsurgical Developments Foundation (rat model for use in teaching microsurgical techniques)
Tissuee Transformation Technologies (provider of cells from human tissues)
List of Virtual Dissection Websites
Humane Endpoints In Animal Experiments For Biomedical Research
